NIDHI PRAYAS V1

Department of Science & Technology | Government of India DST | Govt. of India

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2022PC45

Atal Incubation Centre - Centre for Cellular and Molecular Biology (CCMB)

Sr.	Name of the PRAYASEEs	Brief description of the Project
1	Abhishek Gaikar	A improved design for endotracheal tube (ETT) to aid suctioning automation to reduce ventilation associated infection in neonates (can excel to pediatric, adults and geriatric patient group)
2	Ajay Kumar	A novel sleeve design to ease manual handling of conventional metallic retractors, reduce soft internal tissue damage, and early detection of bladder damage.
3	Gurushankar	Bhrunomatra: Smart wearable pregnancy monitoring device/ Need for monitoring pregnancy from second trimester, labor, delivery and post pregnancy for people who are in low resource settings.
4	Roopa Jones Ganji	Development of active recombinant Hyaluronidase in bacterial expression system as a drug delivery adjuvant
5	Shalini Singh	Developing a novel Virus like Particle Platform for bioconjugation of antigens of choice for improving their immunogenicity.
6	Kouduri Devankinandan	Specializing in Negative Pressure Wound Therapy (NPWT), we design innovative devices, advancing wound care technology to promote healing, enhance patient outcomes, and meet diverse clinical needs with a commitment to quality.
7	Suchandrahas Medamalli	Working on revolutionizing asthma management, this solution helps patients track severity, monitor episodes, and report accurately. Physicians gain remote insights, enabling precise treatment, better medication, and improved patient outcomes.
8	Raj Kumar Kunaparaju	Development of a Novel Capillary-Based Oligo Synthesizer for Cost-Effective Gene Synthesis
9	Dr Giriraj Ratan Chandak	Development of REASSURED protocol(s) for genetic diagnosis of musculopathies.
10	Debabrata Jana	Working on overcoming keratinocyte supply limitations, we propose transient, controllable immortalization using self-replicating RNA, enabling scalable keratinocyte production for in vitro skin models without compromising cell properties or transformation.
11	Sumeet Popli	Using paddy straw instead of timber, we create eco-friendly engineered boards with formaldehyde-free binders—an affordable, sustainable alternative to traditional particle board and MDF.

11 innovators in 2022-2023

Sr.	Name of the PRAYASEEs	Brief description of the Project
1	Dr. Ramdas A. Aute	Building a platform for enzymatic synthesis of therapeutic siRNA by replacing the traditional chemical method to produce commercial scale siRNA with significantly less chemical waste and lower costs.
2	Sri Harsha Paladugu	Developing India’s first affordable, plastic-based Organ-on-Chip to replace animal testing, improve drug accuracy, and align with global regulatory shifts like FDA Modernization Act 2.0.
3	Dr Aswathy Menon	The smart inhaler, powered by AI for versatile disease management, offers personalised care, improved drug delivery, enhanced patient adherence, and improved communication with healthcare providers.
4	SATHYABALAN MURUGESAN	Hoynoza’s multiplex diagnostic kit rapidly detects major urogenital infection bacteria, enabling targeted treatment and reducing antibiotic resistance through early, precise identification of gram-positive and negative species.
5	Sumithra M	Milltize Innovations converts millet straw into eco-friendly fiber composite boards, offering a sustainable, biodegradable plywood alternative that supports circular economy and reduces agricultural waste.
6	Ramya Adimulam	Our product washes, dries, sterilizes, and dispenses milk using AI, ML, and IoT—doubling as a health monitor by tracking milk intake and infant wellness.
7	Kamal Prasad	Developing a specific, sensitive, and cost-effective Q-RT-PCR assay to detect Her-2/neu in breast cancer, offering faster, accurate, affordable diagnosis over FISH and IHC.
8	Dr. Ellojita Rout	Revive Limb is a portable device combining oxygen and infrared therapy to heal chronic ulcers, aiming to reduce infections, amputations, and improve home-based wound care.
9	Arjit Saxena	This project creates a ground-based microgravity simulator to enhance disease detection, drug testing, and tissue research, advancing healthcare and supporting space medicine innovations.
10	Karthik Tallapaka	Developing a cost-effective genetic test for Spinocerebellar Ataxias using Oxford Nanopore Technology, enabling multiplexed, decentralized diagnostics in resource-limited settings despite minimal equipment needs.
11	Shital Bhanushali	EnzyChroma is a nature-based biotech hair dye that preserves natural color, offers seamless application, and suits fast-paced lifestyles—succeeding where chemical and natural dyes fail.
12	Jayanti Kumari	OncoALERT is a non-invasive, equipment-free saliva-based test using IL-8 and LGALS3BP biomarkers to enable accurate, point-of-care oral cancer screening with field deployability.

12 innovators in 2024-2025